Search results for "Extra pulmonary"

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LIODetect®TB-ST: Evaluation of novel blood test for a rapid diagnosis of active pulmonary and extra-pulmonary tuberculosis in IGRA confirmed patients

2021

Abstract Because of the current limits of immunological tests in the diagnosis of tuberculosis there is a need to identify new and rapid tests that can be carried out on a large scale in endemic countries and useful in the identification of infected subjects, but also able to discriminate those with latent infection from subjects with active. We have taken into consideration and analysed the LIODetect®TB-ST Tuberculosis Rapid Test, a membrane test for the qualitative detection of specific IgG, IgA, and IgM antibodies against Mycobacterium tuberculosis, performed on serum, plasma, or whole blood.85 samples positive to QuantiFERON TB-GOLD PLUS test were processed using this test and the resul…

AdultMaleMicrobiology (medical)TuberculosisIgm antibodyImmunologyDiseaseSensitivity and SpecificityMicrobiologyQuantiferon TB GoldQuantiFERONMycobacterium tuberculosisExtra pulmonary tuberculosisPLUSHumansTuberculosisMedicineBlood testTuberculosis PulmonaryIFN-γHematologic Testsbiologymedicine.diagnostic_testbusiness.industrySpecific iggMycobacterium tuberculosisMiddle Agedbiology.organism_classificationmedicine.diseaseAntibodies BacterialInfectious DiseasesImmunologyFemalebusinessLIODetect®TB-STInterferon-gamma Release Tests
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Preliminary development of a questionnaire to measure the extra-pulmonary symptoms of severe asthma

2021

Abstract Background Research into the effects of asthma treatments on the extra-pulmonary symptoms of severe asthma is limited by the absence of a suitable questionnaire. The aim was to create a questionnaire suitable for intervention studies by selecting symptoms that are statistically associated with asthma pathology and therefore may improve when pathology is reduced. Methods Patients attending a specialist asthma clinic completed the 65-item General Symptom Questionnaire (GSQ-65), a questionnaire validated for assessing symptoms of people with multiple medically unexplained symptoms. Lung function (FEV1%) and cumulative oral corticosteroids (OCS) calculated from maintenance dose plus ex…

Pulmonary and Respiratory MedicineMalemedicine.medical_specialtyFibromyalgiaSevere asthmaExtra pulmonaryDiseases of the respiratory systemFibromyalgiaInternal medicineAsthma controlForced Expiratory VolumeSurveys and QuestionnairesmedicineHealth Status IndicatorsHumansAsthma Symptoms Fibromyalgia Questionnaire Patient reported outcomesPatient reported outcomesLung functionAsthmaAgedAged 80 and overRC705-779business.industryMaintenance doseQuestionnaireextra-pulmonary symptomsAsthma clinicMiddle Agedmedicine.diseasesparse regressionAsthmarespiratory tract diseasesSymptomslinear regressionFemaleSymptom AssessmentbusinessResearch Article
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A questionnaire to measure the extra-pulmonary symptoms of asthma

2021

Background: Research into the effects of asthma treatments on the extra-pulmonary symptoms of severe asthma is limited by the absence of a suitable questionnaire. The aim was to create a questionnaire suitable for intervention studies by selecting symptoms that are statistically associated with asthma pathology and therefore may improve when pathology is reduced. Methods: Patients attending a specialist asthma clinic completed the 65-item General Symptom Questionnaire (GSQ-65), a questionnaire validated for assessing symptoms of people with functional disorders. Lung function (FEV1%) and cumulative oral corticosteroids (OCS) calculated from maintenance dose plus exacerbations were obtained …

severe asthmamedicine.medical_specialtybusiness.industryEmergency medicinemedicineMeasure (physics)Extra pulmonarybusinessmedicine.diseaseextrapulmonary impactAsthma
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